Bridging to Transplant in Older AML Patients: Old Notions and New Evidence
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Release Date: August 23, 2021
Expiration Date: August 23, 2022
Expected time to complete this activity as designed: 15 minutes
There are no fees for participating in or receiving credit for this online activity.
In this activity, Dr. James M. Foran discusses new concepts in bridging therapy and stem cell transplant in older AML patients. He reviews the safety and efficacy data regarding stem cell transplant in this patient population and explores a number of agents and therapeutic strategies that have been evaluated for bridging to transplant in older AML patients, including midostaurin, CPX-351, decitabine, venetoclax-based regimens, gilteritinib, and the investigational agent Iomab-B.
This activity is designed for multidisciplinary healthcare providers in the community setting, including hematologists, oncologists, nurse practitioners, pharmacists and other allied healthcare professionals who provide care to patients with acute myeloid leukemia.
Upon completion of this educational activity, participants should be able to:
- Understand the barriers that prevent many older adults with AML from undergoing bridging therapy and allogeneic stem cell transplant
- Review agents and therapeutic approaches that have been found to be successful in bridging older AML patients to transplant
- Evaluate and select older patients who would make good candidates for bridging therapy and transplant
Bridging to Transplant in Older AML Patients: Old Notions and New Evidence – James M. Foran, MD
Instructions for Participation and Credit
This activity is eligible for credit through August 23, 2022. After this date, this activity will expire and no further credit will be awarded.
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- Complete the educational content as designed.
- Complete the post-test. To receive a certificate, you must receive a passing score of 70%.
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- Certificates for CME may be printed immediately after successfully completing the post-test and activity evaluation. Pharmacist credit will be uploaded to CPE Monitor 4 weeks following receipt of a completed, qualified form.
James M. Foran, MD
Associate Professor of Oncology
Mayo Clinic College of Medicine and Science
Dr. James Foran received his medical degree from the University of Manitoba Medical School. He continued post-graduate studies as an intern/resident at Beth Israel Hospital; chief medical resident at the Boston VA Medical Center; medical oncology fellow at Dana-Farber Cancer Institute; clinical research fellow at Imperial Cancer Research Fund; and bone marrow transplant fellow at the Royal London School of Medicine. Dr. Foran is currently an Associate Professor of Oncology at Mayo Clinic College of Medicine and Science. In addition, he is a Consultant in both the Division of Hematology/Oncology, Department of Internal Medicine, and the Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Jacksonville, Florida.
Dr. Foran is American Board of Internal Medicine (ABIM) certified in internal medicine and medical oncology, with a certificate of completion of specialist training-UK in medical oncology and Royal College of Physicians of Canada FRCPC (Internal Medicine). He is a member of the Eastern Cooperative Oncology Group and Leukemia and Lymphoma Society. In addition, Dr. Foran is on the editorial board at Clinical Lymphoma and Myeloma, and a reviewer with Annals of Oncology, Biology of Blood and Marrow Transplantation, Blood, Cancer, Journal of Clinical Oncology, and Leukemia and Lymphoma, among others. His major focus is on early phase and investigator-initiated clinical trials in acute leukemia, myelodysplastic syndrome and malignant lymphoma, with collaboration with laboratory-based investigators.
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This activity is supported by educational grants from Bristol-Myers Squibb, Genentech, Helsinn Healthcare SA, and Jazz Pharmaceuticals.
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Dr. James Foran has received honoraria as a consultant for Revolution Medicines, Inc. and honoraria related to formal advisory activities from Bristol-Myers Squibb Company, Novartis AG, Pfizer Inc. and SERVIER. His institution has received grant support related to research activities from AbbVie Inc., Actinium Pharmaceuticals, Inc., Aprea Therapeutics, Aptose Biosciences, Boehringer Ingelheim GmbH, H3 Biomedicine Inc., Kura Oncology, Inc., Takeda Oncology, Trillium Therapeutics Inc., and Xencor.
Planning Committee Disclosures
The individuals listed below from MediCom Worldwide, Inc. reported the following for this activity: Joan Meyer, RN, MHA, Executive Director, Isabelle Vacher, Vice President of Educational Strategy, Lillian McVey, Medical Writer, and Andrea Mathis, Project Manager, have no relevant financial relationships.
Peer Reviewer Disclosure
In accordance with MediCom Worldwide, Inc. policy, all content is reviewed by external independent peer reviewers for balance, objectivity and commercial bias. The peer reviewers have no relevant financial relationships to disclose.